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Treating Psoriasis with UVB Light Therapy

UVB (ultraviolet B) light therapy is a common treatment for psoriasis, a chronic skin condition characterized by the rapid growth of skin cells, leading to red, scaly plaques. UVB light therapy involves exposing the affected skin to controlled doses of UVB light. Here's a quick overview of the process:

1. Consultation: Patients should consult a dermatologist to determine if UVB therapy is suitable for their specific type and severity of psoriasis.

2. Treatment Setup: UVB therapy is typically administered in a specialized dermatologist's office or clinic. The patient's skin is exposed to UVB light, either in a full-body chamber or through a handheld UVB device.

3. Frequency: The frequency and duration of treatment sessions vary based on the patient's condition. Initially, treatments may be brief to

UVB light treatment triggers the production of vitamin D, which is essential for healthy bones and immune system function. It also promotes the growth of new skin cells and reduces inflammation, leading to improvements in conditions such as psoriasis, eczema, and vitiligo. The treatment is usually administered in a medical setting using specialized equipment, and the dosage of UVB radiation is carefully monitored to minimize the risk of side effects such as sunburn or an increased risk of skin cancer. UVB light treatment can be used as a standalone therapy or in combination with other treatments, depending on the specific condition being treated. While the long-term effects of UVB light treatment are still being studied, current evidence suggests that it can be a safe and effective option for managing certain skin disorders.

Psoriasis

Psoriasis is an inflammatory, non-contagious skin disease that sometimes begins in childhood and adolescence, but usually in adulthood, and is usually lifelong. After allergic contact dermatitis and neurodermatitis, it is one of the most common chronic skin diseases.

The typical appearance is sharply defined, scaly reddening of the skin, which occurs primarily on the elbows, the sides of the knees and the hairy head, and is sometimes itchy. This is also indicated by the medical name of the disease, which comes from the Greek "psao" (I scratch). In addition to the skin, psoriasis also affects the joints in 5-10% of sufferers and the nails in about 50%.

Distribution

The

An Update on Narrowband Ultraviolet B Therapy for the Treatment of Skin Diseases

Abstract

High-Throughput RNA Sequencing Reveals the Effect of NB-UVB Phototherapy on Major Inflammatory Molecules of Lesional Psoriasis

https://pubmed.ncbi.nlm.nih.gov/34858799/

Combination of carboxytherapy with NB-UVB leads to higher percentage of repigmentation and patients' satisfaction compared to monotherapy with NB-UVB.

Carboxytherapy has been used in the treatment of autoimmune skin diseases such as psoriasis and morphea. Carboxytherapy has antioxidant effects, and leads to better tissue oxygenation, and release of growth factors. In this article, we decided to evaluate efficacy of combined carboxytherapy and narrowband-ultraviolet B (NB-UVB) compared to NB-UVB alone in the treatment of vitiligo. This is a prospective, split-body double-blind comparative study performed in patients with generalized stable vitiligo in acral areas and extremities referred to dermatology clinic of Afzalipour hospital in Kerman University of Medical Sciences. NB-UVB was performed three times a week in non-consecutive days for 4 months. In each patient, one lesion was randomly treated with carboxytherapy (weekly sessions for total of 16 sessions). Efficacy

Conclusions: PUVA and NB-UVB remain an effective anti-psoriatic treatment;

Introduction: Narrow band ultraviolet B (NB-UVB) and psoralen-ultraviolet A (PUVA) remain inexpensive and effective anti-psoriatic therapies adopted worldwide with different frequency protocols. We aimed to systematically assess the evidence on the effects of different frequency protocols of phototherapy in treating psoriasis.

Evidence acquisition: We used the following terms, namely "photochemotherapy", "phototherapy", "psoriasis", "UVB", "UVA" and "ultraviolet therapy", to search the Cochrane Controlled Register of Trials, MEDLINE and Embase databases on August 1, 2019. We organized results using a PRISM diagram and analyzed bias risks with RoB-2 tool.

Evidence synthesis: We included five randomized controlled trials (RCTs) on oral PUVA and three RCTs on NB-UVB.

Conclusions: Home NB-UVB phototherapy is at least as effective as outpatient clinic NB-UVB phototherapy for the treatment of mild to severe psoriasis (GRADE: Moderate).

People with photoresponsive skin conditions with whom we spoke viewed home NB-UVB phototherapy as beneficial for those with health conditions that make it difficult to travel, for those with busy schedules, and for those who may not have the means to pay for travel to clinics.

Full details here:

https://pubmed.ncbi.nlm.nih.gov/33240453/

Conclusion: Addition of calcipotriene ointment may improve the efficacy of the targeted UVB phototherapy in the treatment of plaque-type psoriasis.

Background: Targeted UVB and topical calcipotriene have frequently been used in the treatment of psoriasis, but the joint effect of calcipotriene and targeted UVB has been controversial.

Objectives: The purpose of this study was to systematically evaluate whether the efficacy of the combined use of targeted UVB and calcipotriene is superior to the targeted UVB alone.

Methods: We performed systematic review and meta-analysis of randomized controlled trials (RCTs) in patients with plaque-type psoriasis through searching the defined key words in the PubMed, EMBase, and Cochrane Central Register databases. Pooled mean difference of the Psoriasis Area and Severity Index (PASI) relative change (%)

Impact of narrow-band ultraviolet B radiation therapy on the quality of life of patients with vitiligo

Conclusion: NB-UVB therapy is effective in alleviating psychological stress and improving the quality of life of patients with vitiligo.

Objectives: Patients with vitiligo experience emotional and psychological stress as they undergo long-term therapy. The debilitating psychosocial effects of this disease on patients' quality of life is well-documented. This study evaluates the effect of the introduction of narrow-band ultraviolet-B (NB-UVB) therapy on the quality of life of patients with vitiligo in Almadinah Almunawwarah, KSA.

Methods: Thirty-eight patients from the main dermatology center of Ohud Hospital, Almadinah Almunawwarah, were interviewed between June 2017 and March 2019 using the Dermatology Life Quality Index (DLQI) questionnaire. The